Background and Aims:
The aim of this study was to compare the neurological severity and diffusion lesion size between acute ischemic stroke involving putamen and corona radiata with perfusion abnormality and without that.
Methods:
We included the patients 1)who were admitted from 2014 to 2018 due to acute ischemic stroke in the putamen and corona radiata, 2) who underwent MR perfusion and MR angiography on admission, 3) whose MR angiography showed neither stenosis nor occlusion of the M1 segment of the middle cerebral artery or the internal carotid artery in the affected side, 4) whose modified Rankin Scale before admission was from 0 to 3. We evaluated patient's baseline characteristics, abnormal findings of MR perfusion, maximum lesion’s diameter on admission, NIHSS, upper limb score of NIHSS.
Results:
Seventy-one patients met our inclusive criteria. Their median age was 75 years. Median MLD on admission was 15mm, median NIHSS on admission was 3 and median NIHSS at discharge was 2,  median upper limb score of NIHSS on admission was 1 and median upper limb score of NIHSS at discharge was 0. Thirty(42%) presented abnormalities of MR perfusion (aMRp) in their ischemic lesions. In patients with and without aMRp, median MLD on admission was 20.5 and 14mm(p=0.0002), median NIHSS on admission was 5 and 3(p=0.07), median upper limb score of NIHSS at discharge was 0.5 and 0(p=0.07), respectively. 
Conclusions:
In patients with abnormal findings of MR perfusion in the putamen and corona radiata on admission, MLD was larger on admission and neurological symptoms were more severe.

ABNORMAL FINDINGS OF MR PERFUSION IN THE PUTAMEN AND CORONA RADIATA PREDICTS MORE SEVERE NEUROLOGICAL IMPAIRMENT IN PATIENTS WITH THE ACUTE ISCHEMIC STROKE