15 yrs old male, BMI 19, with osteosarcoma in left distal femur scheduled for tumour resection and total knee arthroplasty following chemotherapy refused the proposed option of regional continuous neuroaxial anaesthesia. The patient opted for general anaesthesia and
peripheral nerve block for postoperative pain control. 21 yrs old female, BMI 17, with right distal femur osteosarcoma and solitary pulmonary metastasis successfully treated with chemotherapy agreed to spinal anaesthesia with intravenous sedation and peripheral nerve blocks for postoperative pain management. In both cases surgical procedure lasted for four hours and went uneventfully. Peripheral nerve blocks were performed in PACU, immediately after the surgical procedure. Ultrasound guided femoral catheter placement for intermittent femoral nerve block with bolus of levobupivacain 0.25% 15 mL was followed by sciatic nerve
block guided by peripheral nerve stimulator, with 10 mL of 0.5% levobupivacain in both patients. The technique combining continuous femoral with sciatic nerve block proved to be adequate for postoperative pain management after major knee surgery in our two patients

SCIATIC NERVE BLOCK COMBINED WITH FEMORAL NERVE BLOCK IN POSTOPERATIVE PAIN MANAGEMENT AFTER TOTAL KNEE ARTHROPLASTY WITH MEGAENDOPROSTHESIS IN TWO PATIENTS WITH OSTEOSARCOMA