There are many compelling reasons to avoid opioid in the surgical population.  Basic science would suggest that patients undergoing surgery for primary cancer may benefit from avoiding the inmunodepressent effect of opioids.. 
We present 10 case reports of low dose opioid anesthesia undergoing laparoscopic colon surgery. 
Our patients received a low-dose-opiod-anesthesia using  a preincisional loading dose of lidocaine 1.5 mg*Kg, Ketamina 0.5 mg*Kg and Dexametasona 8 mg. 
During surgery a TIVA with Propofol TCI 2,0-2,5, Lidocaine 1 mg*Kg, Ketamine 0.2 mg*Kg*h and a Remifentanil  TCI 2-2.5 was performed.
Before the end of the surgery NSADIS, paracetamol 1g and 0.05 mg*Kg dose of morfine was administered.
As a multimodal analgesia program an interfascial catheter was implanted on the surgical wound that was used during the next 48 h in the postoperative period. 
Result:
The mean VAS after extubation was 0 and also two hours later.  One patient required 3 mg of morphine during his PACU stay.  During the next 48 h after surgery the morphine consumption was zero.
Discussion
This results indicate that opioid sparing anesthesia with lidocaine, ketamine and propofol infusions decresed opioid requirements in the early postoperative period. Prolonged analgesic is obtained with interfascial catheter and NSADIS. It has been reported that infusion of lidocaine in combination with low doses of opioids is associated with reduced intraoperative and postoperative opioid requirements. 
Conclusion
Opioid sparing anesthesia is associated with lower morphine requirements in the early postoperative period.  A multimodal analgesia regimen guarantees the lowest opioid requirement during postoperative period.

Efectivity of low-dose-opioid-anesthesic technique in Colon laparoscopic surgery