Background	
Pain is one of the most prevalent and impairing problems reported by breast cancer survivors, as it results in disabilities on different domains of functioning and severely hamper ones quality of life. Unraveling the multifactorial character of pain yields possibilities to improve current treatment modalities. Therefore, the aim of this study was to determine the degree of pain-related disability and clarify the contribution of associated risk factors for its occurrence in breast cancer survivors.

Methods	
Seventy women who had completed their primary breast cancer treatment were included in this cross-sectional study. The following outcome measures were evaluated as independent variables for their contribution to pain-related disability (measured by the Pain Disability Index, with a maximum score of 70): pain intensity, self-reported signs of central sensitization, fatigue, illness beliefs, pain catastrophizing and kinesiophobia. At first, bi- and multivariable regression methods were conducted. Secondly, a stepwise regression analysis was performed to determine the explained variance of the PDI. 

Results		
Mean score on the PDI was 16 at 4.5 years post-surgery. Multivariable regression analysis revealed higher levels of kinesiophobia as the main contributor to pain-related disability. Ultimately, stepwise regression showed that up to 40% of variance in pain-related disability could be explained by kinesiophobia, negative perceptions related to illness consequences and pain catastrophizing.

Conclusion	
This study shows that breast cancer survivors portray moderate self-reported pain-related disability. Kinesiophobia emerged as the main predictor of pain-related disability at this time point, which could shine a light on the improvement of treatment modalities for pain management in this population.

KINESIOPHOBIA CONTRIBUTES TO PAIN-RELATED DISABILITY IN BREAST CANCER SURVIVORS: A CROSS-SECTIONAL STUDY