High-grade pain in individuals with OA is an independent factor of disease progression. The causal factors of intensive pain, however, remain unclear. To clarify the case, we've undertaken a multicentre prospective study, aiming to understand the relationship between the factors and the development of high-grade knee pain. Discriminant analysis has shown that a significant role in development of intensive knee pain belongs to functional impairment, presence of knee varus, Heberden’s nodules, familial OA and cartilage destruction in the medial tibial compartment was shown.

THE MAJOR RISK FACTORS FOR DEVELOPING INTENSIVE KNEE PAIN IN PATIENTS WITH OSTHEOARTRITIS