Stretch marks, or striae gravidarum (SG), occur frequently during pregnancy, affecting 50-90% of women. SG are characterized by inflammatory environment, alteration of dermal matrix, particularly with disorganization of elastic fibers, and at the cell level, modification of fibroblast contractile properties.
Although not physically dangerous, SG represent a major aesthetic concern for pregnant women. Therefore, there’s a need for efficient topical solutions to prevent development of SG or reduce their severity. We have developed two innovative formula targeting specifically prevention or correction of SG based on the selection of natural patented active ingredients with in vitro demonstrated activities:
For the prevention axis we focused on anti-inflammation and preservation of elastic fibers network, a SG Prevention Cream was formulated with avocado peptides, polyphenol-rich maracuja seed extract and hamamelis virginiana extract. A clinical study has been conducted on 64 women from 4 months of pregnancy to 6 weeks after delivery. The subjects applied the product twice a day during the study period. Results show that the product is well perceived by the women and demonstrate the efficacy on stretch marks prevention.
The correction axis was addressed thanks to actives targeting inflammation, repair process as well as inhibiting fibroblasts contractility. Hence, a SG Correction Serum was formulated with avocado oil, maracuja oil concentrate and hyaluronic acid. Its efficacy on SG (size and roughness) was clinically evaluated in a study conducted on 34 women with recent red stretch marks. The subjects applied the product twice a day during 8 weeks. Results demonstrate that the product is well perceived and has a significant efficacy on SG reduction.
A good understanding of SG pathogenesis together with a specific selection of active ingredients allowed us to develop stretch mark prevention and correction products with clinically proven efficacy.

Targeting inflammation, dermal matrix organization and repair process for efficient prevention and correction of striae gravidarum