Objective: Obstructive sleep apnea (OSA) is one of the systemic risk factors for glaucoma. The purpose of the study was to determine the overall prevalence of sleep apnea among patients with glaucoma.
Design: A systematic review and meta-analysis 	
Participants: Study participants were men and women with any form of glaucoma along with OSA. 
Methods: A systematic literature search was performed using MEDLINE, EMBASE, CINAHL, Clinical Trials.gov, and ProQuest Dissertations and Theses until September 14, 2019. All conferences held through Association for Research in Vision and Ophthalmology, American Academy of Ophthalmology, and Canadian Society of Ophthalmology were also searched until September 14, 2019. Eligible articles were identified by reviewing the retrieved results. Data extracted included the total number of patients with glaucoma and the proportion of glaucoma patients with a cooccurring diagnosis of obstructive sleep apnea. Meta-analysis was done using STATA 15.0.
Results: In total, 498 records were retrieved from multiple databases and an additional 40 records were identified through grey literature search. 9 articles with 1183 subjects were included for analysis. Our meta-analysis results indicated a significant rate of obstructive sleep apnea among glaucoma patients (ES = 0.35; CI: [0.15, 0.56]).
Conclusions: We examine the prevalence of OSA in glaucoma patients and conclude that the prevalence of OSA in glaucoma patients is higher.

Prevalence of obstructive sleep apnea in glaucoma patients: A systematic review and meta-analysis

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