As the body’s primary communication network from one organ to another, the endocrine system requires coordination of dynamic biochemistry from the molecular level to the whole organism. The Heffern lab is seeking to uncover the roles and applications of metals in the endocrine system, and more generally, in the extracellular space. With an interdisciplinary approach and diverse expertise, we are working to gain insight and develop therapeutic solutions to endocrine disorders spanning diabetes, liver disease, and cancer. The work presented here investigates the interaction of metal micronutrients with specific peptide hormones. The studies aim to elucidate which metals may interact with these hormones, how they interact, and the biological and structural consequences of this interaction in both normal physiology and disease states.

Uncovering the interactions of bioavailable metals with extracellular peptide hormones

Macromolecular Chemistry: The Second Century

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ACS Spring 2020 National Meeting & Expo

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.