Normal and pathogenic cells require a menu of metal nutrients for optimal growth, but also strategies to mitigate toxicity associated with misregulated or excessive levels of metals like Fe, Cu and Zn. Cells adjust metal homeostasis mechanisms depending on cell type, local growth conditions, and in response to stress. These situations present opportunities to manipulate cellular metals as therapeutic strategies across a number of diseases. In this presentation I will render a metallocentric view on utilizing small molecules and peptides that leverage unique metallobiology associated with infection to selectively inhibit growth of pathogenic microorganisms. This research has been advanced by a diverse team of students and collaborators over many years. In acknowledgement of the ACS Award for Encouraging Women into Careers in the Chemical Sciences, I will emphasize the many ways in which mentoring researchers leads to desirable outcomes for science.

<b>Award Address.</b> (ACS Award for Encouraging Women into Careers in Chemical Sciences). Infectiously inorganic: Metallocentric and mentoring-centric view of advancing bioinorganic chemistry at the host-pathogen interface

Macromolecular Chemistry: The Second Century

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ACS Spring 2020 National Meeting & Expo

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.

Award Address. (ACS Award for Encouraging Women into Careers in Chemical Sciences). Infectiously inorganic: Metallocentric and mentoring-centric view of advancing bioinorganic chemistry at the host-pathogen interface