Currently, there is a great need for a rapid and sensitive detector, specifically for bacterial pathogens throughout the world. Current diagnostic tests use PCR, which adds both cost and time, resulting in patients having to wait 2-3 days for results after initial testing. There is a need to find a way to shorten this time frame and simultaneously increase the portability of the device so that testing can be done within the field. Utilizing rapid LSPR sensing, we hope to achieve both of those goals. Through functionalization of single stranded DNA probes on gold nanoparticles, our method will directly sense for infectious strands of Chlamydia on portable plastic substrates. In the future, we hope to incorporate these sensors in a multiplexed array so that negative and positive control sites can be monitored simultaneously.  In addition, multiple bacteria pathogens can be tested alongside one another in a portable, sensitive, rapid manner. <br/>

Rapid, sensitive plasmonic sensor of chlamydia without DNA amplification

Macromolecular Chemistry: The Second Century

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ACS Spring 2020 National Meeting & Expo

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.