Electrochemistry has gained interest as a possible method for the investigation of antioxidants over the last several decades.  Recent work in our group has focused on integrating electrochemical techniques into routine analysis of antioxidant and lipid degradation, specifically omega-3 fatty acids due their frequent supplementation into health and consumer goods.  To improve the versatility of our methods, various solvents have been investigated as a potential replacement for our initial solvent system which utilized benzene, a known carcinogen and mutagen.  Finding less hazardous solvents would allow our methods to be utilized in industry along with providing the option for the development of a transportable all-in-one instrument.  To this extent, organic solvents including hexanes, ethanol, isopropanol, acetonitrile, and isooctane were investigated at various ratios in an effort to optimize our figures of merits while reducing the hazards associated with our experimentations.  The antioxidants sesamol (novel natural antioxidant), butylated hydroxytoluene (leading synthetic antioxidant), and rosemary extract (leading natural antioxidant) were analyzed in pure organic solvent (100%), 1:1, and 1:2/2:1 ratios of the solvents listed above.  Limits of detection, lower limits of quantitation, linear range, and Pearson correlation coefficient will be presented for all three antioxidants as determined from each solvent system.  Preliminary results show that 2:1 solvents systems with ethanol as the major constituent provide similar, or in certain instances better, figures of merit than the previous benzene solvent system.<br/>

Effects of less hazardous solvents on the figures of merit for sesamol, butylated hydroxytoluene, and rosemary extract via electrochemical analysis

Macromolecular Chemistry: The Second Century

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ACS Spring 2020 National Meeting & Expo

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.