3-MCPD and glycidyl esters in edible oils are contaminants that are formed through refining processes and several of these substances have been classified as possible human carcinogens. Methods, which are similar to one another, have been developed by ISO, AOCS, and DGF for analyzing these contaminants. While the method cover extraction and derivatization techniques in detail, very little attention is paid to the GC-MS methods. With emerging automated systems, it is important to simplify and speed up the method by optimizing the parameters, to include switching to split injection.<br/>The initial optimization of the temperature program led to an 8-minute decrease in the analysis time and additional time can be saved by utilizing free method development software. The employment of split injection resulted in better peak shape and achieved limits of detection that were comparable to splitless injection. Further evaluation of split injection revealed that the same performance is achieved regardless of inlet temperature resulting in greater flexibility for different inlet configurations.

Optimizing GC-MS and GC-MS/MS analysis of 3-MCPD and glycidyl esters

Macromolecular Chemistry: The Second Century

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ACS Spring 2020 National Meeting & Expo

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.