Silver insertion into titania offers a number of tangible advantages compared with transition metal oxides, when applied as nano-biocidal agents. These advantages relative to titania are effectiveness under visible light conditions, lower minimum bactericidal concentrations (MBC), lower incorporation of silver (relative to silver nanoparticles) and broad range of activity. Three concentration-dependant trends are observed, at very high nanoparticles (&gt; 50,000 ppm) concentrations, cellular lysis is observed, similar to that for bleach, suggesting that lipid oxidation is the major form of inactivation; at intermediate levels (MBC: 2.5 ppm to 20 ppm) inhibition is observed with minimal lysis, suggesting that other mechanisms, such as DNA fragmentation, protein and respiration inhibition or disruption of the membrane potential are more prominent in inactivating the microbe than lysis and at ultralow doses (&lt; 2.5 ppm) bacteriostatic like phenomenon is observed, suggesting some membrane damage inhibiting growth, but not extensive enough to case cellular inactivation. Plausible mechanism of inactivation is offered to explain the observed events. Lastly, other advantages common with transition metal oxides are retained, such as long-term persistence and 100% metal recycling. Collectively, this approach can be applied where traditional disinfectant approaches are ineffective such as with antibiotic resistant bacteria, high sunlight where bleach is rapidly oxidized and has many potential benefits to the community in terms of a microbe-free water supply.

Progressive approach on inactivation of bacteria using nanostructured composites

Macromolecular Chemistry: The Second Century

[Author Benefits](https://scimeetings.acs.org/?utm_source=pubs_content_marketing&utm_medium=website&utm_campaign=0320_MCF_NPI_Launch_Spring_Homepage&ref=pubs_content_marketing)

[How to use SciMeetings](https://storage.googleapis.com/dl.morressier.com/acs/SciMeetings-ACSSpring2020-HowToGuide_M3020-Final.pdf)

[Frequently Asked Questions](https://storage.googleapis.com/dl.morressier.com/acs/SciMtng_ACSNMSp2020_FAQ_M3120_Final.pdf)

ACS Spring 2020 National Meeting & Expo

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.