5-hydroxymethylfurfural (5HMF) is one of the molecules considered as a platform for obtaining chemical products from lignocellulosic biomass. Obtaining 5HMF can be done quite efficiently by dehydrating fructose, however, fructose is not abundant. For this reason, the transformation of glucose, the most abundant hexose contained in lignocellulosic biomass, to fructose is a very important step in the process of obtaining 5HMF. The isomerization reaction is catalyzed by acidic Lewis type centers. MOF (Metal Organic Frameworks) are composed of metals coordinated to organic compounds that form a 3D structure which can act as Lewis acids. In this work the use of four different MOF catalysts with different cations and structure have been studied. The reaction was performed in stirred tank reactors in a Mettler Toledo Easy Max® equipment. A solution of 1% glucose (0.05g) in 5mL of GVL-10%H2O was used and 0.08g of catalyst (MIL-101(Cr), Cu-BTC, MIL-53(Al) or Fe-BTC) was added. The reactions were carried out at 140°C for different reaction times and were analyzed by HPLC. The fructose yield obtained is compared to the reaction time for the MIL-101(Cr), Cu-BTC, Fe-BTC and MIL-53(Al) catalysts. In all the catalysts the fructose formation is observed, while in an experiment without catalyst the formation of fructose was not observed. Clearly, the catalyst with the highest fructose yield is MIL-101(Cr), reaching a value of 22% after 1 hour of reaction and being of the highest data described in bibliography remaining constant for a longer time. The Cu-BTC and MIL-53(Al) catalysts showed a similar profile of constant growth of fructose yield versus time, although with lower values than with MIL-101(Cr). The Fe-BTC catalyst is the one that shows a different behavior, at short times it has a fructose yield of 12%, which decreases at longer times, everything seems to indicate that this catalyst requires short times to produce the highest yield of fructose under these reaction conditions and at longer times the fructose gives rise to the formation of other compounds. These results are compatible with what has been observed with homogeneous catalysts described in the literature in which chromium salts are the most efficient compounds in the glucose-to-fructose isomerization.

Study of the isomerization of glucose to fructose using MOF (metal organic frameworks) catalysts

Macromolecular Chemistry: The Second Century

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ACS Spring 2020 National Meeting & Expo

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.