Nanoparticles fabricated by colloidal solution routes offer several benefits over traditional catalytic materials, including a high surface area/mass ratio and a well controlled size distritbution and morphology that in many cases leads to improved activity and selectivity. Unfortunately, state-of-the-art colloidal nanoparticle synthesis is cost-prohibitive because it remains a bench-scale manual process. Scaling these syntheses via traditional reactor scale-up is limited by the lack of thermal and mixing uniformity in industrial-scale reactors. On the other hand, millifluidic reactors provide excellent thermal uniformity and facilitate droplet flows that allow for excellent microscale mixing. In our recent work, we have shown that millifluidic reactors are capable of producing catalytically active particles from both precious and base transition metals as well as metal alloys, phosphides, and carbides. Reactions can be performed at high temperatures (&gt; 300 °C) using both conventional and microwave heating. Millifluidic reactors are easily adaptable to sustainable ionic liquid solvents that can be recycled, further lowering process cost. We have also pursued the use of parallelization to increase the throughput of millifluidic systems. This work includes the development of a 16-channel reactor with inline process monitoring that is capable of approaching liter-per-hour reactant throughputs. Together, this work shows that continuous millifluidic manufacturing is a promising technique for lowering the cost of colloidal nanoparticles by automating the synthesis process and facilitating scale-up by reactor parallelization.

Scalable synthesis of catalytic nanomaterials by millifluidic continuous flow manufacturing

Macromolecular Chemistry: The Second Century

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ACS Spring 2020 National Meeting & Expo

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.