Diets today are normally high-heat processed foods that contain high levels of AGEs. Advanced Glycation End Products, better known as AGEs, are harmful compounds that form when proteins (as well as lipids and nucleic acids) react with sugar. AGEs can accumulate in the body via two pathways, internally through natural biochemical pathways and dietary intake. Dietary advanced glycation end products (dAGEs) are linked to the formation of several diseases associated with older age, such as diabetes, cardiovascular disease, cancer, etc. This project looks to expand on reported dAGEs found in pork chops prepared using different cooking techniques (raw, boiled, pan seared, slow cooked, and microwaved), and suggest different approaches to reduce the amount of AGEs through dietary intake. In this research, we analyzed the meat samples for quantity of Nδ-(carboxylmethyl)-L-lysine (CML) and Nδ-(carboxylethyl)-L-lysine (CEL), two well studied AGEs. Studies have shown that an increase in CML and CEL contribute to the formation and progression of tumors, and diabetes through the activation of oxidative stress. We hypothesize that the quantity of CML and CEL found in the pork chops will follow previous reports and will be reduced when cooking at lower temperatures, for shorter time periods, and in moist environments. Therefore, we expect to find the raw meat to contain the least amount of CML and CEL, followed by the boiled, slow cooked, microwaved and pan seared samples. The Gas Chromatography- Mass Spectroscopy (GCMS) was used to determine the amount of CML and CEL in the prepared pork chop samples. Results indicated a larger amount of CEL in both raw and boiled sampled (32.57, 51.56) compared to CML (1.31, 0.65). These findings were surprising since the structures of CEL and CML are similar, we believed their values would be similar in similarly prepared pork chop samples.

Determination of AGEs in meat products

Macromolecular Chemistry: The Second Century

[Author Benefits](https://scimeetings.acs.org/?utm_source=pubs_content_marketing&utm_medium=website&utm_campaign=0320_MCF_NPI_Launch_Spring_Homepage&ref=pubs_content_marketing)

[How to use SciMeetings](https://storage.googleapis.com/dl.morressier.com/acs/SciMeetings-ACSSpring2020-HowToGuide_M3020-Final.pdf)

[Frequently Asked Questions](https://storage.googleapis.com/dl.morressier.com/acs/SciMtng_ACSNMSp2020_FAQ_M3120_Final.pdf)

ACS Spring 2020 National Meeting & Expo

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.