We will present our results to authenticate the compositional profile indicated for a broadly marketed commercial rice bran arabinoxylan product (reportedly used in some 40 published studies) that is asserted to function as an immune system activator. There is no information on the chemical composition and structural profiles of the commercial product independent of the manufacturer. We are interested in how rice bran arabinoxylan and materials derived from it may modulate innate immune function at the intestinal epithelial barrier to regulate nutrient uptake, while maintaining protective response to pathogens and inflammatory signals. We described previously at ACS AGFD our rice bran arabinoxylan materials and preliminary results showing T84 colonocytes treated with them increased tight-junction protein levels. We hypothesized the commercial functional food product would be rich in branched arabinoxylan oligosaccharides, which we intended to isolate and compare with our material for evaluation in the colonocyte bioassay. In evaluation of the oligosaccharide profiles by MALDI-TOF MS and the monosaccharide composition by GC-FID for five product brands, we determined all contained only negligible quantities of arabinoxylan. This is astonishing considering the clinical implications for this product.

Compositional profiles of commercial rice bran arabinoxylan products used for immune system activation

Macromolecular Chemistry: The Second Century

[Author Benefits](https://scimeetings.acs.org/?utm_source=pubs_content_marketing&utm_medium=website&utm_campaign=0320_MCF_NPI_Launch_Spring_Homepage&ref=pubs_content_marketing)

[How to use SciMeetings](https://storage.googleapis.com/dl.morressier.com/acs/SciMeetings-ACSSpring2020-HowToGuide_M3020-Final.pdf)

[Frequently Asked Questions](https://storage.googleapis.com/dl.morressier.com/acs/SciMtng_ACSNMSp2020_FAQ_M3120_Final.pdf)

ACS Spring 2020 National Meeting & Expo

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.