Diseases caused by plant pathogenic bacteria have attained great concern worldwide as they are responsible for severe economic losses throughout the cultivated areas. Moreover, antibiotic resistance in plant-pathogenic bacteria has become a problem in pathosystems where these antibiotics have been used for many years. Therefore, its critical the development of robust strategies to ensure the safe and effective control of critically important plant diseases. Bio-nanotechnology takes a prominent part in agriculture through approaches for the management of resistance of plant pathogenic bacteria. Due to their high level of organization, phages represent elaborate bio-nanomachines that have been optimized by nature over millions of years. They consist of numerous components that are assembled into a complex architecture. These bio-nanomachines are proposed as bacterial population control alternatives to antibiotics. This research, four bacteriophages were collected from the northwest region of Mexico. These phages survived the isolation, purification, and storage processes. The phages exhibited lytic activity against P. syringae, R. solanacearum, X. euvesicatoria and E. amylovora. Genome analysis suggests that the phages are strictly lytic without carrying genes associated with virulence factors and/or potential immunoreactive allergen proteins. The bacteriophages isolated in this study has shown promising results in the biocontrol of bacterial growth under in vitro conditions, suggesting that it may prove useful as an alternative agent for the control of bacterial plant pathogens. However, further oral toxicity testing is needed to ensure the safety of phage use.

Antimicrobial bio-nanomachines to controlling plant pathogenic bacteria

Macromolecular Chemistry: The Second Century

[Author Benefits](https://scimeetings.acs.org/?utm_source=pubs_content_marketing&utm_medium=website&utm_campaign=0320_MCF_NPI_Launch_Spring_Homepage&ref=pubs_content_marketing)

[How to use SciMeetings](https://storage.googleapis.com/dl.morressier.com/acs/SciMeetings-ACSSpring2020-HowToGuide_M3020-Final.pdf)

[Frequently Asked Questions](https://storage.googleapis.com/dl.morressier.com/acs/SciMtng_ACSNMSp2020_FAQ_M3120_Final.pdf)

ACS Spring 2020 National Meeting & Expo

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.