The analysis of polar ionic pesticides in surface and drinking water as well as food and beverages has become a controversial issue in recent years. The development of genetically modified organism (GMO) crops tolerant to glyphosate (N-(phosphonomethyl)glycine) and glufosinate ((RS)-2-amino4-(hydroxy(methyl)phosphonoyl)butanoic acid), for example, promoted the use of these broad spectrum herbicides. In addition, glyphosate is used as a crop desiccant and to suppress weeds in parks and at roadsides. Consequently, polar pesticides are found in foods as residues and in the environment as contaminants of surface waters and soils. There are concerns about their potential adverse effects on human health such as their potential carcinogenicity, although latest toxicological assessments do not predict toxicological risks for humans under normal conditions of human or environmental exposures. Current regulations set maximum levels of glyphosate and its metabolite AMPA (α-amino-3-hydroxy5-methyl-4-isoxazolepropionic acid) at 100 ng/L in drinking water. In food and beverage samples, generally higher maximum residue levels (MRL) apply, ranging from 10 µg/kg for food intended for consumption by children up to hundreds of mg/kg in other matrices. The analysis of glyphosate and other polar compounds presents a difficult analytical challenge. The aim of this work was to develop and validate an IC-MS/MS method for direct analysis of polar ionic pesticides, under toutine conditions.

Routine analysis of polar pesticides in water at low ng/L levels by ion chromatography coupled to triple quadrupole mass spectrometer

Macromolecular Chemistry: The Second Century

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ACS Spring 2020 National Meeting & Expo

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.