Nanotechnology provides new innovative solutions for original as well as generic applications in a wide variety of industries including pharmaceuticals, agrochemicals, cosmetics, foods, nutraceuticals and home care. This technology has led to the creation of nano-formulated drugs, which have unique supramolecular structures with improved clinical utility such as increased exposure, reduced or eliminated food effect, changed administration route. The novel supramolecular structures can deliver substantial improvements in material properties and biological performances, such as: solution like behaviour that ensures optimal systemic exposure; substantial increase in apparent solubility facilitating the compound availability of absorption; unique absorption mechanism that does not require traditional dissolution processes and results in improved drug absorption. Using novel bottom-up nanoparticle pharmaceutical delivery technology, called SpeedyNano™, that relies on controlled continuous-flow precipitation, we have adapted this technology for the preparation of several nano-agrochemicals. The properties of the produced nanostructured particles could be modified during the process by the precise control and optimization of various reaction parameters (e.g. temperature, flow rate, pH and concentration). Using specific industrial examples, we will demonstrate that the above technology demonstrates the following advantages: Increased solubility in the spray tank Increased solubility leads to better coverage of contact pesticides on plant surface Improved leaf/cuticle penetration leading to vastly improved efficacy Increased biological activity enable the reduction of application rates Lower application rates reduce environmental load/leeching while not compromising effective pest control Lower application rates also reduce pre-harvest intervals or pesticide residue levels in the harvested crop Our presentation will cover a description of the technology and the process, followed by the field results from the application of several nano-herbicides, fungicides, and insecticides.

Development of novel nanostructured agrochemicals to enhance solubility and reduce

Macromolecular Chemistry: The Second Century

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ACS Spring 2020 National Meeting & Expo

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.