One of the biopolymers, DNA has recently emerged as a building block because it is abundant in nature, shows a liquid crystal phase depending on the concentration and can be functionalized by electrostatic interaction. Controlling the orientation of DNA molecules is positively necessary for utilizing DNA as a building block and forming the micro- or nanostructures. Therefore, we developed a technique to control the orientation of particles in a thin film by using shear stress, evaporation-induced self-assembly and bulk elastic properties of DNA liquid crystal phase. The technology can easily control the orientation of DNA in a large area, but there is a limitation that only simple one-dimensional structures appear on a microscopic level. High-order pattering is required for designing the structure with building blocks and using as organic electronics, inorganic particle array, and other lithographic templates. To fabricate complicated two-dimensional micro- or nanostructures of this soft material, a predesigned template can be applied for confinement. On the template, due to the interaction between the elastic properties of the DNA and the confinement effect of the substrate, a unique and complex structure can be formed spontaneously. Here, we conducted the shear-induced experiments on square-shaped micro-channel substrates to form sophisticated DNA nanostructures and the pattern of the DNA can be modulated by channel spacing. Also, it can transfer the anisotropy to other nanomaterials as a two-dimensional polymer matrix and alignment layer. This will help to understand the self-assembly of DNA molecules by confinement effect can provide applications to bio-template for nanoparticles, rod-like liquid crystals or other biomaterials.

Shear and evaporation-induced two-dimensional microstructure of DNA polymer on the topographic pattern

Macromolecular Chemistry: The Second Century

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ACS Spring 2020 National Meeting & Expo

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.