A series of both mono- and biscationic quaternary ammonium compounds (QACs) bearing metallocene moieties were efficiently synthesized from aminometallocene precursors. The resulting amphiphiles were tested for antimicrobial activity against a set of Gram-positive and Gram-negative bacteria, including some known to bear QAC resistance genes, in an attempt to assess the utility of metal-containing bisQAC amphiphiles as antiseptics.

Metallocene-based multiQACs: Novel metal-containing amphiphilic antiseptics

Macromolecular Chemistry: The Second Century

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ACS Spring 2020 National Meeting & Expo

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.