Infections from Mycobacterium tuberculosis (Mtb) are a major public health threat. The recent discovery that functionalized trehalose analogs can be metabolically incorporated into the mycomembrane of Mtb using Ag85 has led to several new classes of trehalose-based compounds with diagnostic and therapeutic potential. Ths poster will describe our recent efforts to design and biologically evaluate a novel class of trehalose-based photosensitizers for targeting Mtb via photodynamic activation using Mycobacterium smegmatis (Msmeg).

Trehalose-based photosensitizers for targeting Mycobacterium tuberculosis

Macromolecular Chemistry: The Second Century

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ACS Spring 2020 National Meeting & Expo

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.