Disorders of the Central Nervous System (CNS) are alarmingly increasing as the human population is gradually aging. With this concern, CNS disorders affect people of all race, gender, and ages. Diseases such as epilepsy, addiction, bipolar disorder, and Parkinson’s are causes for major concern and research to treat and possibly prevent these diseases.<br/>Carbohydrates are one of the most abundant natural chemical compounds. They are known for their availability as well as their versatility when it comes to applications and synthesis. We propose to synthesize carbohydrate derivatives via glycals, to surpass the blood brain barrier in hopes of treating CNS disorders. We will be building positive results from previously synthesized compounds. Our research consists of preparing modified carbohydrates that bear more robust 4,6-acetal derivatives. Derivatives synthesized will be tested in receptor and animal models for CNS disease.

Synthesis of carbohydrate analogs as potential CNS therapeutic agents

Macromolecular Chemistry: The Second Century

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ACS Spring 2020 National Meeting & Expo

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.