People are consistently exposed to different concentrations of biological and non-biological particles. Aerosol and dust are currently understudied, despite their potentially significant role as a cause of infectious and allergenic adverse health effects. This is especially true for indoor dust and aerosol as people spend majority (∼90%) of their lifetime in indoors. Indoor air quality in palliative care is important as the center optimizes quality of life by anticipating, preventing, and treating suffering when “curative” therapies are futile. Indoor air quality is affected by resuspension/deposition of hospital dust with their aerodynamic size or/and particle type, and further influenced by different activities (e.g., cleaning).  In this work, the MTT Assay was used to determine the cell proliferation rate and the reduction in cell viability of the collected fine particulate matter/dust samples. Reactive oxygen species was quantified by fluorogenic probes for measuring generalized oxidative stress in cells. Energy-dispersive X-ray spectroscopy (EDX) was applied for elemental analysis and chemical characterization of the samples. Bacteria and mold suspended in air (bioaerosol) and deposited on surface (dust) were identified and compared in order to deduce the location characteristics. Further chemical analysis was performed to identify chemical components by using gas chromatography–mass spectrometry and thermal gravimetric analysis. Bioassays such as acute toxicity and estrogenicity were used to distinguish the differences in the present/absent of disinfectant and the sample characteristics at different locations.

Identification and bio-reactivity of chemical components of indoor dust and aerosol in palliative care clinic

Macromolecular Chemistry: The Second Century

[Author Benefits](https://scimeetings.acs.org/?utm_source=pubs_content_marketing&utm_medium=website&utm_campaign=0320_MCF_NPI_Launch_Spring_Homepage&ref=pubs_content_marketing)

[How to use SciMeetings](https://storage.googleapis.com/dl.morressier.com/acs/SciMeetings-ACSSpring2020-HowToGuide_M3020-Final.pdf)

[Frequently Asked Questions](https://storage.googleapis.com/dl.morressier.com/acs/SciMtng_ACSNMSp2020_FAQ_M3120_Final.pdf)

ACS Spring 2020 National Meeting & Expo

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.