Phakellin belongs to the pyrrole–imidazole family of marine sponge derived alkaloids which contain intriguing structural features and potent bioactivities. We are involved in development of a novel and effective method to synthesize phakellin and its analogues from Imidazoformimidamide chemistry. This method provides a simple way to prepare the tricycle ring and can be used to prepare more complex members of the Phakellin family. The progress will be presented.

Studies towards synthesis of phakellin and its analogues such aza- and bis-aza- indolo phakellins

Macromolecular Chemistry: The Second Century

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ACS Spring 2020 National Meeting & Expo

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.