Nitrogen-vacancy (NV) centers in diamond are a promising platform for quantum sensing technologies. These atom-like systems hosted in the diamond crystal can be optically addressed to detect changes in magnetic field, electrochemical potential, and temperature. Furthermore, nanodiamonds (NDs) have low cytotoxicity, enabling their use in biological media. This motivates the development of a method to conjugate reporter molecules directly to the nanodiamond surface to enable site-specific quantum sensing. Modified Boehm titration methods and Fourier-transform infrared (FTIR) spectroscopy were used to confirm presence and activation of nanodiamonds’ surface carboxyl groups, and various buffer systems were tested to determine nanodiamond compatibility for amine-group conjugation.

Characterizing conjugation of primary amines to diamond nanoparticles

Macromolecular Chemistry: The Second Century

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ACS Spring 2020 National Meeting & Expo

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.