Supramolecular polymer-based structures rely on reversible, non-covalent interactions (i.e. hydrogen-bonding and electrostatic interactions) to facilitate the molecular self-assembly of larger structures from nanoscopic to macroscopic. Supramolecular polymer hydrogels represent an exciting class of materials with a wide range of potential applications, particularly in the biomedical fields. In this work, polymers are prepared by RAFT polymerization using a modified chain transfer agent that enables polymer end-functionalization with nucleosides. Based on Watson-Crick base-pairing, the inclusion of nucleoside end-groups facilitates specific hydrogen-bonding interactions between polymer chains that have complementary base pairs. More specifically, this work focuses on the impact of polymer chain length and monomer chemistry on the properties of supramolecular hydrogels.

Supramolecular structures composed of nucleoside functionalized polymers prepared by RAFT polymerization

Macromolecular Chemistry: The Second Century

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ACS Spring 2020 National Meeting & Expo

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.