19F NMR is a powerful and versatile tool to study protein structure and protein–ligand interactions due to the favorable NMR characteristics of the 19F atom, its absence in naturally occurring biomolecules, and small size. 19F atoms can be introduced readily into proteins and ligands, permitting to use them as 'beacons' to study interactions by NMR. Both, ligand and protein resonances can be exploited for this purpose. I will discuss several applications, involving 19F-modified proteins and 19F-containing ligands, demonstrating the awesome power of 19F NMR.

Award Address (E. Bright Wilson Award in Spectroscopy sponsored by the E. Bright Wilson Endowment). The awesome power of Fluorine NMR

Macromolecular Chemistry: The Second Century

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ACS Spring 2020 National Meeting & Expo

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.