The ability to rapidly transform a substrate from a hard, structural material to a soft, hydrogel structure over the course of a few tens of nanometers makes polymers elegant materials for tailoring the biology-materials interface. The use of amphiphilic block copolymers to form surface brushes provides most of the benefits of “grown from” polymer brushes with the ability to coat large area surfaces. Surfaces used for anti-fouling coatings are an example of brush like, large area application. Prior studies have shown that amphiphilic brush surfaces (with both polar and non-polar groups) provide a broad range of anti-fouling properties. Here we describe new approaches to surface active block copolymers and discuss strategies to tune surface properties and surface placement while introducing active units that interfere with the biochemistry of fouling. Polymers are made by living anionic polymerization and modified using “click” chemistry.

Amphiphilic block copolymers to tailor the biology-materials interface

Macromolecular Chemistry: The Second Century

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ACS Spring 2020 National Meeting & Expo

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.