BindingDB (www.bindingdb.org) is the first publicly accessible database of experimental protein-small molecule binding data. In recent years, we have focused our curation efforts on patent data, as these are not, to our knowledged, handled by any other similar database. In particular, although SureChEMBL’s automated curation extracts many compounds from patents, it does not provide affinity data for these compounds. In addition, it is easier to extract data from US patents than from scientific articles, for several reasons. Indeed, semi-automation of the process of curating binding data from US Patents has allowed us to process over 1,000 US Patents a year, leading to extraction of &gt;200,000 affinity data for &gt;100,000 compounds during the 12-month period from Nov 1, 2018 to October 31, 2019 (http://bindingdb.org/bind/ByPatent.jsp). I will discuss the curation process and the data, as well as recent enhancements to the BindingDB user interface aimed at improving the viewing format as well as query and browsing capabilities.

Advances in data curation and the user interface at BindingDB

Macromolecular Chemistry: The Second Century

[Author Benefits](https://scimeetings.acs.org/?utm_source=pubs_content_marketing&utm_medium=website&utm_campaign=0320_MCF_NPI_Launch_Spring_Homepage&ref=pubs_content_marketing)

[How to use SciMeetings](https://storage.googleapis.com/dl.morressier.com/acs/SciMeetings-ACSSpring2020-HowToGuide_M3020-Final.pdf)

[Frequently Asked Questions](https://storage.googleapis.com/dl.morressier.com/acs/SciMtng_ACSNMSp2020_FAQ_M3120_Final.pdf)

ACS Spring 2020 National Meeting & Expo

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.