Synthetic anion receptors have important applications in sensor technologies, as potential therapeutics for anion transport diseases, and for removal of harmful phosphates and nitrate in our waterways as a result of farmland stormwater runoff. In both natural systems and the majority of synthetic systems, anion binding typically occurs through traditional hydrogen-bond donor groups such as polarized O-H and N-H functionalities. Recent advancements have led to the development of size-dependent macrocyclic anion receptors that utilize non-traditional polarized C-H hydrogen-bond donor groups to bind anions. These macrocyclic receptors are pre-organized to bind specific, small anions with high affinity. Our research focuses on the development non-macrocyclic C-H anion receptors with the flexibility to bind much larger anionic species. We describe the synthesis and anion binding studies of triphenoxymethane-based anion receptors that utilize non-traditional C-H hydrogen bonding.

Synthesis of triphenoxymethane-based anion receptors utilizing nontraditional C-H bonds

Macromolecular Chemistry: The Second Century

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ACS Spring 2020 National Meeting & Expo

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.