Persister cells are a subset of a bacterial population that is tolerant to antibiotic treatment. Persisters evade degradation and eradication via antibiotics due to their tolerance to them, allowing them to survive otherwise lethal doses. Unlike antibiotic-resistant mutants, persisters do not grow in the presence of antibiotics and do not pass on their persistence to subsequent generations. However, once the antibiotic has been removed, they can continue to grow like normal. Persistence is a rare phenotype, with 1% or less of cells becoming persisters depending on bacterial strain and growth conditions. Persisters may play a prominent role in recurrent, chronic infections and the development of antibiotic resistance. Treatments for combating persistent bacteria are needed, and compounds that act against them are being investigated. Essential oils may be a promising source of such compounds. Essential oils are natural compounds extracted from some plants, and many have been shown to exhibit antimicrobial properties. In this study, the effect of tea tree oil (TTO) on bacterial persisters was characterized.<br/>

Effect of tea tree oil on bacterial persisters

Macromolecular Chemistry: The Second Century

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ACS Spring 2020 National Meeting & Expo

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.