A metal free and redox-neutral, method for Beckmann rearrangement, employing inexpensive and widely available SO<sub>2</sub>F<sub>2 </sub>gas, is described. The reported room temperature transformation is compatible with wide array of sterically and electronically diverse aromatic, heteroaromatic, and lignin model oximes to afford amides in good to excellent yields. The reaction proceeds through the formation of an imidoyl fluoride intermediate that can also be used for synthesis of amidines.

Sulfuryl fluoride mediated synthesis of amides from ketoximes via Beckmann rearrangement

Macromolecular Chemistry: The Second Century

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ACS Spring 2020 National Meeting & Expo

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.