The oxidation of alcohols is a common and time-honored class of reaction in synthesis. Classical oxidation reactions have used pyridinium chlorochromate, Jones reagent, sodium dichromate, and Swern conditions as effective oxidation reagents. In recent years, there has been growing interest in the use of supported reagents in tandem with these reactions, particularly with silica gel towards Cr-based oxidizing agents. Although there are plenty of reactions carried out in silica gel reported in the literature, the use of sand in reactions remains limited. Comparing between sand and silica gel, both are SiO2, crystalline, and porous, yet silica gel is more widely used. Herein, we report some of our results regarding the oxidation of primary and secondary alcohols to aldehydes and ketones using ammonium dichromate in the presence of washed sand. Using toluene or acetonitrile for primary and secondary alcohols respectively, the clean oxidation of these alcohols into aldehyde and ketone forms is observed based on TLC, 1H and 13C-NMR of the crude material. Comparison on the preparation of aldehydes and ketones using the developed reaction to solvent-free and sand-free reactions will be discussed.

Oxidation of primary and secondary alcohols into aldehydes and ketones using ammonium dichromate in sand

Macromolecular Chemistry: The Second Century

[Author Benefits](https://scimeetings.acs.org/?utm_source=pubs_content_marketing&utm_medium=website&utm_campaign=0320_MCF_NPI_Launch_Spring_Homepage&ref=pubs_content_marketing)

[How to use SciMeetings](https://storage.googleapis.com/dl.morressier.com/acs/SciMeetings-ACSSpring2020-HowToGuide_M3020-Final.pdf)

[Frequently Asked Questions](https://storage.googleapis.com/dl.morressier.com/acs/SciMtng_ACSNMSp2020_FAQ_M3120_Final.pdf)

ACS Spring 2020 National Meeting & Expo

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.