Siderophores interact with surfaces of minerals like iron oxides. In contrast to iron, titanium is not considered as bioactive partly due to the insolubility of Ti(IV) in water, but siderophores do bind to and sometimes demineralize TiO2 surfaces. Titanium’s role in biology and the environment is overlooked, despite the significant role it can play to be bioactive. However, recent studies are ongoing to investigate its bioavailable nature. A hydroxamic acid siderophore like desferrioxamine B (DFOB) is used to study the adhesion and dissolution mechanism of Ti(IV) from TiO2. In situ ATR-FTIR spectroscopy is used to study dissolution for different Ti minerals (rutile, anatase) with a variation of concentration and pH. Vibrational modes involving C=O stretching and N-H stretching are found due to the interaction of DFOB with Ti(IV). ICP-OES and UV-vis are also used to determine the metal concentration in solution after dissolution. Surface chemistry between these minerals and siderophore could be used as a setting to observe the bioactive nature of titanium. Although titanium is considered inert, it has significant applications in many cases, so it is very important to understand its biological role in the environment.

Siderophore binding to TiO2 surfaces probed by ATR-FTIR

Macromolecular Chemistry: The Second Century

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ACS Spring 2020 National Meeting & Expo

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.