While protein-based therapeutics have become the predominant new approach for treatment of disease, delivery challenges associated with these more complex molecules have recently come into harsh relief. Many successful technologies for delivery of small molecule drugs have been described, including nanoparticle-based methods that succeed in passing the digestive tract and in targeting specific tissues. Incorporation of biopolymers, i.e. proteins, for which maintenance of structural stability is critical for function has, however, remained difficult. The current study aims to develop a novel technology for overcoming this barrier and establishing a foundation for protein-based drug delivery. We are testing a biocompatible mixture of surfactants composed of 10MAG (decylmononacyl glycerol) and LDAO (lauryldimethylamino-N-oxide) with biocompatible solvents to determine which formulations show strong potential for drug encapsulation coupled with minimal toxicity to the cell populations tested.

Development of a new biocompatible vehicle for delivery of protein therapeutics

Macromolecular Chemistry: The Second Century

[Author Benefits](https://scimeetings.acs.org/?utm_source=pubs_content_marketing&utm_medium=website&utm_campaign=0320_MCF_NPI_Launch_Spring_Homepage&ref=pubs_content_marketing)

[How to use SciMeetings](https://storage.googleapis.com/dl.morressier.com/acs/SciMeetings-ACSSpring2020-HowToGuide_M3020-Final.pdf)

[Frequently Asked Questions](https://storage.googleapis.com/dl.morressier.com/acs/SciMtng_ACSNMSp2020_FAQ_M3120_Final.pdf)

ACS Spring 2020 National Meeting & Expo

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.