Antibiotics are commonly administered to fish raised in hatcheries to treat or prevent infectious diseases. The Oregon Department of Fish and Wildlife (ODF&W) would like to use carcasses of spawned fish as nutrients along the banks of rivers. However, there are no data that demonstrate that the antibiotics are completely depleted by the time the fish are placed in the environment. In this study, we developed a method of analysis to determine the concentration of the antibiotic tulathromycin in fish kidney tissues based on liquid chromatography with UV detection (LC-UV). The method was then utilized to conduct depletion studies in salmon. Kidney tissues from fish injected with tulathromycin at varying intervals of time were analyzed to determine how long it takes for the tulathromycin to be completely depleted. If successful, this will become an ongoing study that will involve hundreds of samples from a large population of fish from surrounding hatcheries.

Determination of tulathromycin in fish tissue by liquid chromatography with UV detection

Macromolecular Chemistry: The Second Century

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ACS Spring 2020 National Meeting & Expo

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.