Catalytic functionalization of carbon–hydrogen bonds offers potential applications in many fields including the conversion of simple hydrocarbons (e.g. benzene) to higher-value chemicals. However, challenges remain in the field of catalytic C–H activation of hydrocarbons. Thus, efforts have been devoted to developing fundamental understanding of key steps required for C–H activation, and strategies to accelerate this process. A series of (RPNP)Rh carboxylate complexes (RPNP = 2,6-bis-{(di-R-phosphino)methyl}pyridine, R = tert-butyl, iso-propyl, cyclohexyl) were synthesized and used for testing the effects of various additives in catalytic hydrogen–deuterium exchange of toluene-d8 with weak protio-acidic media (acetic acid) monitored by 1H NMR spectroscopy. Additives with oxidizing properties such as Cu(OAc)2 and AgOAc were found to facilitate the C–H activation of toluene by stabilizing the active catalysts against decomposition through the formation of inactive elemental rhodium.

Additive effects in catalytic arene C–H activation: Studies of Rh catalysts supported by bis-phosphine pincer ligand

Macromolecular Chemistry: The Second Century

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ACS Spring 2020 National Meeting & Expo

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.