Thioaurones are the sulfur analogues of aurones and they have enjoyed a wide range of applications: they are used in the dyes and cosmetics fields, and as photoswitchable materials in electrophotography, but have also been reported to be cytotoxic to cancer cells. Unlike aurones, their biological properties have not been thoroughly investigated. In order to determine whether or not thioaurones can be used as medical imaging dyes, we are attempting to synthesize a series of thioaurone derivatives in order to understand the effect various substituents may have on the spectroscopic properties of the conjugated donor-acceptor chromophore system.

Synthesis and physical organic study of thioaurones

Macromolecular Chemistry: The Second Century

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ACS Spring 2020 National Meeting & Expo

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