A simple method used to prepare dimethyl 2,2'-(5-amino-4,4,6-tricyano-3-methylcyclohexa-1,5-diene-1,3-diyl) diacetate was successfully done through mixing methyl acetoacetate, malononitrile in presence of piperidine. Another pathway procedure was also obtained the same product with adding aliphatic aldehyde. Compound’s structure investigates by various techniques; such as: FTIR, 1HNMR, 13CNMR, mass and single crystal structure analysis. The compound is being estimated for anti-inflammatory and antifungal activities. The results showed that the compound with the molecular formula of C16H16N4O4 crystallized in the Monoclinic, Pc, a = 6.4194 (14)  Å, b = 9.374 (2) Å, c = 13.071 (3) Å, β = 98.761 (7)°, V = 777.4 (3) Å3, Z = 2. The propose mechanism for this reaction will be described.

Synthesis and structure investigation of dimethyl 2,2'-(5-amino-4,4,6-tricyano-3-methylcyclohexa-1,5-diene-1,3-diyl) diacetate obtained using one pot reaction

Macromolecular Chemistry: The Second Century

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ACS Spring 2020 National Meeting & Expo

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.