Engineers at the highly specialized manufacturing facility, the Kansas City National Security Campus (KCNSC), have increased their efforts to develop more efficient methods of chemical production via flow chemistry and microfluidic technologies. By converting batch processes to flow, reaction parameters such as residence time, degree of mixing, and reaction temperature are more controllable. Additionally, this allows for increased opportunities for in-line workup, decreasing technician effort and increasing reproducibility. Diphenylmethylsilanol (DPMS) is used as a hydrogen blowing agent in the production of siloxane foams. Previous work has been completed to synthesize DPMS at the KCNSC via lab-scale batch reaction. Recently, this process was translated to flow chemistry and optimized for product purity and throughput. This poster will focus on the translation of the DPMS synthesis to flow and the subsequent optimization steps.

Converting silanol synthesis from batch production to flow via microfluidics

ACS Fall 2020 Virtual Meeting

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.