Allowing many chemical reactions to be completed within minutes, microwave technology has revolutionized preparative chemistry. Since it is a green technology, it is becoming widely adopted in both academic and industrial laboratories. Heterocycles are very important functional groups especially in medicinal chemistry. In this research heterocyclic precursors of pharmaceuticals are synthesized using microwave radiation. In this poster we describe the synthesis of a number of 2,4,5-trisubstituted imidazoles from 1,2-diketones and substituted benzaldehydes in the presence of NH<sub>4</sub>OAc. The imidazoles are purified and characterized using FTIR and NMR. These imidazoles were tested as possible catalysts in microwave synthesis of esters.

Green chemistry synthesis of imidazoles from 1,2-diketones

ACS Fall 2020 Virtual Meeting

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