ABSTRACT<br/>The study of medicinal plant and other natural products have played vital impact in the development of medicinal chemistry, biosynthesis and mechanism of biological action as well as providing medically useful compounds. This study evaluated the presence of flavonoid in three well known medicinal plants using gas chromatography coupled mass spectroscopy method (Agilent GC-MS, 7890A coupled with MDS 5975C). The flavonoid fraction of the Pteridium aquilinum, Mucuna puriens and Vernonia amygdalina were gotten using solvent treatment and fractionation technigue and then subjected to GC-MS for characterization of individual flavonoid. Twenty nine (29) compounds were found in Pteridium aquilinum with bezene, 1-ethyl -3methyl (22.85), benzene 1,2,3 trimethyl (21.07), n-hexadecanoic acid (5.14) and phytol (3.13) been the highest. Mucuna puriens revealed 14 flavonoid compounds with Octadecanoic acid (10.54), cis vaccenic acid (20.70), phytol (6.28) and n-hexadecanoic acid (33.07) as the highest while Vernonia amygdalina has 23 compound with 9,12,15 octadecatrienoic acid (25.87), n-hexadecanoic acid (21.24), cis vaccenic acid (6.83) and 9,12,15 octadecatrien-1-ol (5.40) as the highest occurring flavonoid. The study showed that Pteridium aquilinum has the highest number of flavonoids followed by Vernonia amygdalina then Mucuna puriens though all the three plant has appreciated number of flavonoid which validate their continuous use in the treatment of diseases.<br/> <br/>

Gc-ms characterization of isolated flavonoid fractions of pteridium aquilinum, mucuna puriens and vernonia amygdalina

ACS Fall 2020 Virtual Meeting

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