When most people think of cannabis and THC they are referring to delta 9 THC but less is known about its analogue delta 8 THC. Delta 8 THC has been shown to be antiemetic, anxiolytic, appetite stimulating, analgesic, and to have neuro-protective properties. Delta 8 THC is similar to delta 9 THC, as it binds to the cannabinoid G-protein coupled receptor CB1 located in the central nervous system, but has less of the undesired inebriation or sedation that is commonly seen in delta 9 THC. The lack of inebriation while still maintaining the medicinal benefits of delta 9 THC could show delta 8 THC to be a more effective medication for patients that require the analgesic and appetite stimulating effects and don’t want to feel tired during the day. This presentation will introduce delta 8 THC though its synthesis and pharmacology. Additionally it will compare and contrast the differences and similarities to delta 9 THC.

Synthesis and pharmacology of delta 8 THC

ACS Fall 2020 Virtual Meeting

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