1. Breaking new barriers with jetted Protein A resins Focusing on dynamic binding capacity, buffer consumption, process economy, and productivity, Purolite have designed a novel range of agarose resins using their proprietary jetting technology. Resins include high capacity Protein A resins as well as a variety of ion exchange resins that are well suited for both continuous and intensified batch processes. In many cases the combination of new resins and cost-effective process designs can bring down the resin cost by more than 75 %.  2. Time to change you resin  Improvements have been made to Protein A base matrices, coupling chemistry, and the ligand itself to improve flow properties, selectivity, capacity and resistance to harsh cleaning methods. However, manufacturers have been reluctant to implement changes because of the complexity of filing processes. We discuss hypothetical and real-life approaches that have been taken to introduce changes and how to take advantage of these improvement opportunities, bringing benefits to manufacturers and patients alike. 3. Praesto Jetted A50 and MabSelect SuRe LX resin lifetime study Bristol Myers Squibb1 and Purolite Life Sciences2 1. Jie Chen, Ronald Maurer, James Angelo, Xuankuo Xu,  2. Sabrina Koch, Mark Hicks, Hans J Johansson A direct comparison of the performance of two resins under similar condition over 100 purification cycles: Praesto Jetted A50 from Purolite Life Sciences and MabSelect SuRe LX from GE Healthcare.

Breaking new barriers with jetted Protein A resins(1), Time to change your resin(2), and (3)Praesto Jetted A50 and MabSelect SuRe LX resin lifetime study.

ACS Fall 2020 Virtual Meeting

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.