This talk describes an assembly-based approach for fabricating multifunctional pyramidal core-shell nanoparticles (CNPs).  CNPs are synthetically-derived structures composed of a dielectric core and metallic shell. Although these structures have tunable optical properties, incorporating cores with additional characteristics (eg. superparamagnetism) is not facile because it requires different synthetic approaches to produce the metallic shell.  We are addressing this limitation using ordered assembly to fill fabricated metallic pyramidal particles with the desired core material. Our approach lacks the chemical constraints of synthesis and can incorporate a range of materials, potentially forming CNPs with several desired functions. CNPs composed of SiO2 or PS cores have been generated and we are currently applying our assembly method to core materials with superparamagnetic (Fe3O4) or fluorescent (rhodamine-dyed PS) properties. Because our method can incorporate materials with multiple functionalities, these fabricated CNPs have the potential to enable multiple therapeutic modalities.

Fabrication and characterization of multifunctional pyramidal core-shell nanoparticles

239th National Meeting (2010)

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