Currently, the development of bimodal imaging contrast agents is highly desirable. By combining magnetic resonance with biological targeting, clinical applications, such as the management of human coronary artery disease, can be investigated by identifying lesions through magnetic resonance imaging and plaque by biomarkers. Si nanoparticles are non-toxic and have excellent photo-stability making them a prime candidate for use in optical imaging. Mn, a paramagnetic element, is used as the dopant for magnetic resonance. In this research, a direct synthesis approach was taken. A solid-state reaction of MnNaSi was reacted with SiI4 to produce manganese doped silicon nanoparticles. The nanoparticles were capped through silanization. Finally, the product was characterized via photoluminescence and UV-visible absorption.

Synthesis of Mn doped Si nanoparticles for biological imaging

239th National Meeting (2010)

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