A luminescence-based sensing approach using �smart� hydrogels and an environment-sensitive luminophore is described. The �smart� hydrogels swell and contract in response to the analyte, bringing about a change in the local environment of an embedded luminophore.  Changes in emission intensity and wavelength allow for real-time and quantitative measurement of the analyte of interest.  The approach is versatile since it can be adapted readily to numerous analytes with modifications to the hydrogel, it affords control of dynamic range by alteration of polymer composition, and it allows for measurement in vapor or aqueous phase.  Results are presented for prototype, thin film sensors constructed from pH, glucose, and lactate-responsive hydrogels, and recommendations are made for application of the sensing methodology to other environmentally and biologically significant analytes.

Biological sensors based on “smart” hydrogels and an environment-sensitive luminophore

239th National Meeting (2010)

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