Inhalation is considered the most relevant route of exposure to induce respiratory infections in experimental animals, as it mimics human exposure to airborne pathogens. However, the delivery of infectious microorganisms via inhalation requires the characterization of many variables, including the selection of bacterial strains and the effect of aerosolization on bacterial survival. The main goal of this project was to characterize different E. coli strains by assessing their growth dynamics, the presence/absence of flagella, and their ability to resist an induced stress. The results obtained in this project will be used to select which E. coli strains will be utilized to assess the effect of aerosolization on bacterial survival.

Characterization of <i>E. coli</i> strains for inhalation studies

239th National Meeting (2010)

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Characterization of E. coli strains for inhalation studies